Cajun Slow Cooked Brisket Recipe

Cajun Slow Cooked Brisket is super flavorful and tender and the perfect dish to serve for a brunch or backyard barbecue.

Cajun Spiced Brisket - Traditional smoked barbecue wagyu beef brisket offered as top view on an old cutting board with Louisiana sauce and salad with tomatoes

Cajun Spiced Slow Cooked Brisket

Course: Main, Main Course
Cuisine: American, cajun, creole, New Orleans, Southern
Prep Time: 10 minutes
Cook Time: 7 hours 20 minutes
Resting time: 10 minutes
Total Time: 7 hours 30 minutes
Servings: 8 servings
Calories: 216 kcal
Author: Kelly D
Searing and lightly smoking the brisket on the grill first and finishing it in the slow cooker makes this the perfect easy dish for a special brunch or dinner.


Cajun Spice Mix

Honey Barbecue Sauce

Print

Ingredients

Brisket Rub:

  • Cajun Spice Mix cajun spice mix recipe link in notes or use your favorite
  • 1/4 cup brown sugar

For the Brisket

  • 1 1/2 lbs beef brisket
  • 3/4 Cup Homemade Honey Barbecue Sauce recipe link in notes or use your favorite bottled sauce
  • 3 T Worcestershire sauce
  • 2 T Tabasco
  • 1/2 sweet onion sliced into rings
  • Mesquite Wood chips soaked in water

Instructions

  1. Mix Cajun spice mix and brown sugar together in a bowl; rub evenly over the surface of the brisket.
  2. Put the brisket in a large, resealable plastic bag; refrigerate 30 minutes to overnight.
  3. Place smoker box with water soaked mesquite wood chips. Preheat grill to high - about 500 degrees. Sear Cajun Spice rubbed brisket over very high heat until outside is well charred, about 10 minutes.
  4. Stir barbecue sauce, Tabasco and Worcestershire sauce together in the bottom of a slow cooker.
  5. Lay brisket into the sauce mixture.
  6. Arrange onions atop the brisket.
  7. Cook on Low until brisket is very tender, 6 to 7 hours.
  8. Rest brisket 10 minutes before slicing or shredding; serve with sauce from the slow cooker.

Recipe Notes

 

 

Alternative Searing and Smoke Method:

 

If you don't have access to a grill, you can sear the brisket in a skillet on the stovetop. To add the smokey flavor - add a tablespoon of liquid smoke and 2 tablespoons of smoked paprika.

 

 

Cajun Spice Mix

 

Homemade Honey Barbecue Sauce

 

Nutrition Facts
Cajun Spiced Slow Cooked Brisket
Amount Per Serving
Calories 216 Calories from Fat 54
% Daily Value*
Total Fat 6g 9%
Saturated Fat 2g 10%
Cholesterol 52mg 17%
Sodium 494mg 21%
Potassium 432mg 12%
Total Carbohydrates 20g 7%
Sugars 17g
Protein 18g 36%
Vitamin A 1.2%
Vitamin C 5.4%
Calcium 3%
Iron 12.5%
* Percent Daily Values are based on a 2000 calorie diet.

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